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Seite 2/2

TRUS- and CT-„Image Fusion“ in the Postplanning Procedure after
Transperineal Permanent Interstitial Seedimplantation (TPSI) of “Low Risk” Prostate Cancer

Block, T.1; Zimmermann, F.2; Czempiel, H.1
1Urologische Praxis und Medizinphysik Vaterstetten,
2Klinik für Strahlentherapie und Radioonkologie, Technische Universität München

Introduction:

In the CT-scan it is difficult to determine the prostate volume exactly, especially in the apical and basal regions. Therefore, the fusion of CT scans (identification of seeds) with TRUS images (determination of prostate volume) were examined 30 days after TPSI in order to analyse the reliability of the postplanning procedure.


Patients/Method:


30 patients (66,9±7,0 years) underwent TPSI (125-I-RAPID Strands®) because of low risk prostate cancer (cT1-2 Gleason Score <7 iPSA <10 ng/ml). 30 days after TPSI a CT scan and a TRUS-volumetry (5 mm increments, lithotomy position) were performed. After calibration CT- and TRUS-images were overlapped (dosimetry-software: PSID 3.5). During image-fusion the first orientation was carried out at the pubic arch and further on at the seminal vesicles, special seed locations and central prostate regions.

CT-/TRUS-Image Fusion
CT-/TRUS-Image Fusion


Histogram Data



Results:


Conclusion:

The fusion of CT- and TRUS-images did not lead to a significant change of prostate volume at day 30 after TPSI. But, however, differences of D90 and V100 were found in the online- and fusion-planning. This is due to altered anatomy structures in CT- and TRUS-examination (pressure of the ultrasound probe on anterior rectal wall). This technique allows a reliable postplanning procedure after TPSI and is less expensive than MRT-image fusion.

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